Patrick Dempsey

According to "Grey's Anatomy" star Patrick Dempsey, no one can take Katherine Heigl's place on the popular show.

"Extra" caught up with the TV doc at the Long Beach Toyota Grand Prix on Saturday, where as one of the celebrity drivers, he went from McDreamy to McSpeedy at 150 miles per hour!

Reese Witherspoon revealed a star-studded film she has coming out next year. "I have this movie I just finished with Owen Wilson, Paul Rudd and Jack Nicholson. I'm very excited about that." But Reese was hush-hush on her collaboration with Pixar, only confirming that it exists. "Yes, I have a movie I'm doing with Pixar."

Lauren Conrad has a few things lined up as well. "I'm writing a couple of books, I've been working with Kohl's department store, and when I get home I'm meeting with some writers for my movie."

The night ended with the lone man in the bunch, Patrick Dempsey, giving word on how things at "Grey's Anatomy" are going this season. "It's been great. The writers have really changed the format on how they are presenting the show. It's fresh." And what about the women of "Grey's"? Dempsey had the answer. "The girls are growing up. They're no longer girls, they're women, with children, and it's a great thing to see."

"Extra" was first on set of the new season of "Grey's Anatomy" -- and we have the inside scoop straight from Patrick Dempsey!

When we last saw the docs at Seattle Grace, Derek and Meredith tied the knot with a Post-It note and gave up their extravagant wedding so Izzie could walk down the aisle instead. Dempsey tells "Extra" he was shocked when he read the script. He says, "I think the fans are expecting a wedding. I was surprised too, like this is it? This is what it's gonna be?"

Patrick tells us he would have like to Ellen Pompeo's real-life pregnancy written into the script for a "Grey's" McDreamy baby! He adds, "I think it would've been interesting to see her juggling a career and baby." Ellen and husband Chris Ivery are expecting their first child this winter.

Season 6 of "Grey's Anatomy" premieres September 24 on ABC.

Love is in the air for aunt-niece team Julia and Emma Roberts -- as the gals share the silver screen for the first time!

Superstar Julia and niece Emma -- who got her big break in the 2007 flick "Nancy Drew" -- are teaming up in the comedy "Valentine's Day," scheduled for a 2010 release.

Their A-list co-stars include Jessica Alba, Jessica Biel, Bradley Cooper, Patrick Dempsey, Jennifer Garner, Ashton Kutcher and Shirley MacLaine.

These Hollywood stars just keep getting hotter! Check out "Extra's" gallery of male stars who are Hot and Over 40!

"Grey's Anatomy" hunk Patrick Dempsey watches the timing screens in his team's garage before qualifying for the 77th running of the Le Mans 24 Hour race in France.